Your colleague has come up with an idea to devise a gene therapy for cervical cancers with HPV.
Your colleague has come up with an idea to devise a gene therapy for cervical cancers with HPV. His idea is to introduce a wild-type copy of the gene encoding the p53 gene into the HPV infected cancer cells.Will this work?Explain why or why not.
Solution Preview
No.It won’t work because any p53 protein made will be degraded as a result of HPV. Since Human papilloma Virus(HPV) infection is associated with cervical cancer,you obtain a HPV infected cancer cell line and a corresponding uninfected normal cell lin
