Question: You determine that a particular gene in a peson with a genetic disease is the same size as that of a healthy individual.
Question: You determine that a particular gene in a peson with a genetic disease is the same size as that of a healthy individual. You suspect that the arises from a point mutation (a single nucleotide change that results in a defect in the protein) Describe a how you could confirm this hypothesis.
Comment: We learned about Sanger Sequencing and Next Gen sequencing in class. Could you use either of these and if yes why would you use one over the other
Solution Preview
Point mutations that occur in non-coding sequences are usually without any results, although there are exceptions. If the mutated base pair is in the promoter sequence of a gene, then the expression of the gene could change If the ba..
